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Legit in the sense of being available for purchase is not the same as regulated, tested, or effective

Apply a new patch daily

GLP-1 receptor agonists are large protein molecules exceeding 3,000 Daltons in molecular weight, far above the 500 Dalton threshold for effective passive skin penetration

Patients seeking GLP-1 therapy should only obtain medications through legitimate healthcare channelsprescribed by a registered healthcare professional and dispensed by a General Pharmaceutical Council (GPhC) or Pharmaceutical Society of Northern Ireland (PSNI) registered pharmacy

Patients should maintain a rotation schedule and visually inspect previous application sites for persistent redness, itching, or skin changes that might indicate an adverse reaction

The theoretical mechanism involves transdermal absorption of GLP-1 analogs or related compounds through the skin's stratum corneum into systemic circulation